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MACC1 Polyclonal Antibody

Rabbit Anti-MACC1 Polyclonal Antibody

Product Specifications

Background

MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409) -HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al. 2009 [PubMed: 19098908]) .

CAS Number

9007-83-4

Product Name Alternative

MACC1; Metastasis-associated in colon cancer protein 1; SH3 domain-containing protein 7a5

Gene ID

346389

Accession Number

Q6ZN28

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human MACC1

Clonality

Polyclonal

Tag

Metastasis-associated in colon cancer protein 1

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

97kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

MACC1 Polyclonal Antibody detects endogenous levels of MACC1 protein.

Observed Molecular Weight

97

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.

Other Product Names

MACC1; Metastasis-associated in colon cancer protein 1; SH3 domain-containing protein 7a5

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q6ZN28

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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