Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

DPYD Polyclonal Antibody

Rabbit Anti-DPYD Polyclonal Antibody

Product Specifications

Background

Dihydropyrimidine dehydrogenase [NADP (+) ] encoded by DPYD is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene.

CAS Number

9007-83-4

Product Name Alternative

DPYD; Dihydropyrimidine dehydrogenase [NADP (+) ]; DHPDHase; DPD; Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenase

Gene ID

1806

Accession Number

Q12882

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human DPYD

Clonality

Polyclonal

Tag

Dihydropyrimidine dehydrogenase [NADP (+) ]

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

120kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

DPYD Polyclonal Antibody detects endogenous levels of DPYD protein.

Product Datasheet

https://www.abbkine.com/datasheet/ABP52958.pdf

Observed Molecular Weight

120

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-300; ELISA 1:20000; IF 1:50-200

Other Product Names

DPYD; Dihydropyrimidine dehydrogenase [NADP (+) ]; DHPDHase; DPD; Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenase

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q12882

Isotype

Rabbit IgG

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Hps3-set siRNA/shRNA/RNAi Lentivector (Mouse)
23873094 4 x 500 ng

Hps3-set siRNA/shRNA/RNAi Lentivector (Mouse)

Ask
View Details
H1N1 Hemagglutinin 1 Rabbit pAb
E47R2001 100 µL

H1N1 Hemagglutinin 1 Rabbit pAb

Ask
View Details
Pit-1 (D-7) AC
sc-393943 AC 500 µg/mL - 25% ag

Pit-1 (D-7) AC

Ask
View Details
Rabbit Polyclonal ZNF462 Antibody [Biotin]
NBP1-78192B 0.1 mL

Rabbit Polyclonal ZNF462 Antibody [Biotin]

Ask
View Details
Cdk5r2 Mouse shRNA Plasmid (Locus ID 12570)
TR514331 1 Kit

Cdk5r2 Mouse shRNA Plasmid (Locus ID 12570)

Ask
View Details
Mouse Monoclonal PIH1D2 Antibody (OTI4A10) [DyLight 350]
NBP2-73403UV 0.1 mL

Mouse Monoclonal PIH1D2 Antibody (OTI4A10) [DyLight 350]

Ask
View Details