Scn4b Polyclonal Antibody

Rabbit Anti-Scn4b Polyclonal Antibody

Product Specifications

Background

Sodium channel subunit beta-4 encoded by SCN4B is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10) . Three protein-coding and one non-coding transcript variant have been found for this gene.

CAS Number

9007-83-4

Product Name Alternative

SCN4B; Sodium channel subunit beta-4

Gene ID

6330

Accession Number

Q8IWT1

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human Scn4b at AA range: 30-110

Clonality

Polyclonal

Tag

Sodium channel subunit beta-4

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

27kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Scn4b Polyclonal Antibody detects endogenous levels of Scn4b protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200