PSCA Polyclonal Antibody

Rabbit Anti-PSCA Polyclonal Antibody

Product Specifications

Background

PSCA encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. PSCA is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. PSCA includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

PSCA; Prostate stem cell antigen

Gene ID

8000

Accession Number

O43653

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human PSCA at AA range: 10-90

Clonality

Polyclonal

Tag

Prostate stem cell antigen

Applications

WB, ELISA, IHC

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

29kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

PSCA Polyclonal Antibody detects endogenous levels of PSCA protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000