PKR1 Polyclonal Antibody

Rabbit Anti-PKR1 Polyclonal Antibody

Product Specifications

Background

PROKR1 encodes a member of the G-protein-coupled receptor family. prokineticin receptor 1 binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. Prokineticin receptor 1 is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. Prokineticin receptor 1 may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in PROKR1 may be associated with recurrent miscarriage.

CAS Number

9007-83-4

Product Name Alternative

PROKR1; GPR73; PKR1; Prokineticin receptor 1; PK-R1; G-protein coupled receptor 73; G-protein coupled receptor ZAQ; GPR73a

Gene ID

10887

Accession Number

Q8TCW9

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the N-terminal region of human PKR1 at AA range: 30-110

Clonality

Polyclonal

Tag

Prokineticin receptor 1

Applications

WB, IF, ELISA, IHC

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

45kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

PKR1 Polyclonal Antibody detects endogenous levels of PKR1 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IF/ICC1:100-500; ELISA 1:5000-20000; IHC 1:100-500