PAR4 Polyclonal Antibody

Rabbit Anti-PAR4 Polyclonal Antibody

Product Specifications

Background

The tumor suppressor WT1 represses and activates transcription. Pro-apoptotic WT1 regulator encoded by PAWR is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. Pro-apoptotic WT1 regulator is specifically upregulated during apoptosis of prostate cells.

CAS Number

9007-83-4

Product Name Alternative

PAWR; PAR4; PRKC apoptosis WT1 regulator protein; Prostate apoptosis response 4 protein; Par-4

Gene ID

5074

Accession Number

Q96IZ0

Reactivity

Human, Mouse, Rat, Cow

Immunogen

Synthesized peptide derived from the C-terminal region of human PAR4 at AA range: 260-340

Clonality

Polyclonal

Tag

PRKC apoptosis WT1 regulator protein

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

36kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

PAR4 Polyclonal Antibody detects endogenous levels of PAR4 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200