Lyciumin A

Lyciumin A, a cyclic octapeptide, exhibits inhibitory activity on proteases, renin and angiotensin-converting enzyme. Lyciumin A can be used for the research of hypertension[1][2].

Product Specifications

CAS Number

[125708-06-7]

UNSPSC

12352005

Target

Angiotensin-converting Enzyme (ACE) ; Renin

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/lyciumin-a.html

Purity

99.0

Solubility

10 mM in DMSO

Smiles

O=C([C@@H](NC([C@@H](NC(CNC1=O)=O)CO)=O)CC2=CN(C3=C2C=CC=C3)[C@@H](NC([C@@H](NC([C@H]4N(CCC4)C([C@@H]5NC(CC5)=O)=O)=O)CC6=CC=C(C=C6)O)=O)C(N[C@H]1C(C)C)=O)O

Molecular Formula

C42H51N9O12

Molecular Weight

873.91

References & Citations

[1]Kersten RD, et, al. Gene-guided discovery and engineering of branched cyclic peptides in plants. Proc Natl Acad Sci U S A. 2018 Nov 13;115 (46) :E10961-E10969.|[2]Rubin GM, et, al. Recent advances in the biosynthesis of RiPPs from multicore-containing precursor peptides. J Ind Microbiol Biotechnol. 2020 Oct;47 (9-10) :659-674.