MRP3 Polyclonal Antibody

Rabbit Anti-MRP3 Polyclonal Antibody

Product Specifications

Background

Canalicular multispecific organic anion transporter 2 (ATP binding cassette subfamily C member 3) encoded by ABCC3 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . Canalicular multispecific organic anion transporter 2 is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of Canalicular multispecific organic anion transporter 2 has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

CAS Number

9007-83-4

Product Name Alternative

ABCC3; CMOAT2; MLP2; MRP3; Canalicular multispecific organic anion transporter 2; ATP-binding cassette sub-family C member 3; Multi-specific organic anion transporter D; MOAT-D; Multidrug resistance-associated protein 3

Gene ID

8714

Accession Number

O15438

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human MRP3 at AA range: 940-1020

Clonality

Polyclonal

Tag

Canalicular multispecific organic anion transporter 2

Applications

WB, IHC

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

170kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

MRP3 Polyclonal Antibody detects endogenous levels of MRP3 protein.

Observed Molecular Weight

170

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300