Gα olf Polyclonal Antibody

Rabbit Anti-Gα olf Polyclonal Antibody

Product Specifications

Background

GNAL encodes a stimulatory G protein alpha subunit which mediates odorant signaling in the olfactory epithelium. Guanine nucleotide-binding protein G (olf) subunit alpha couples dopamine type 1 receptors and adenosine A2A receptors and is widely expressed in the central nervous system. Mutations in GNAL have been associated with dystonia 25 and this gene is located in a susceptibility region for bipolar disorder and schizophrenia. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

GNAL; Guanine nucleotide-binding protein G (olf) subunit alpha; Adenylate cyclase-stimulating G alpha protein; olfactory type

Gene ID

2774

Accession Number

P38405

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human Gα olf at AA range: 10-90

Clonality

Polyclonal

Tag

Guanine nucleotide-binding protein G (olf) subunit alpha

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

40kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Gα olf Polyclonal Antibody detects endogenous levels of Gα olf protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200