BMP-8A Polyclonal Antibody

Rabbit Anti-BMP-8A Polyclonal Antibody

Product Specifications

Background

BMP8A encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in development of the reproductive system. BMP8A may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1.

CAS Number

9007-83-4

Product Name Alternative

BMP8A; Bone morphogenetic protein 8A; BMP-8A

Gene ID

353500

Accession Number

Q7Z5Y6

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the C-terminal region of human BMP-8A at AA range: 230-310

Clonality

Polyclonal

Tag

Bone morphogenetic protein 8A

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

45-55kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

BMP-8A Polyclonal Antibody detects endogenous levels of BMP-8A protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.