Impromidine

Impromidine (SKF 92676) is a potent agonist for histamine H2 receptor. Impromidine induces gastric mucosal blood flow and acid secretion[1][2].

Product Specifications

CAS Number

[55273-05-7]

Product Name Alternative

SKF 92676

UNSPSC

12352005

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/impromidine.html

Solubility

10 mM in DMSO

Smiles

N=C(NCCCC1=CN=CN1)NCCSCC2=C(C)N=CN2

Molecular Formula

C14H23N7S

Molecular Weight

321.44

References & Citations

[1]Durant GJ, et al. Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors. Nature. 1978 Nov 23;276 (5686) :403-5. |[2]McIsaac RL, et al. Gastric mucosal blood flow and acid secretory changes in man with impromidine: a new specific histamine-H2-receptor agonist. Gut. 1981 Jul;22 (7) :529-33.