SMC1B rabbit pAb

Structural maintenance of chromosomes 1B (SMC1B) Homo sapiens SMC1L2 belongs to a family of proteins required for chromatid cohesion and DNA recombination during meiosis and mitosis (3: Revenkova et al. 2001 [PubMed 11564881]). [supplied by OMIM, Mar 2008],

Product Specifications

Background

Structural maintenance of chromosomes 1B (SMC1B) Homo sapiens SMC1L2 belongs to a family of proteins required for chromatid cohesion and DNA recombination during meiosis and mitosis (3:Revenkova et al., 2001 [PubMed 11564881]) .[supplied by OMIM, Mar 2008]

UniProt

Q8NDV3

Swiss Prot

Q8NDV3

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 110-190

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

135kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

135kD

Fragment

IgG

Subcellular Location

Nucleus . Chromosome . Chromosome, centromere . Associates with chromatin. In prophase I stage of meiosis, localizes along the AE of synaptonemal complexes. In late-pachytene-diplotene, the bulk of protein dissociates from the chromosome arms probably because of phosphorylation by PLK, except at centromeres, where cohesin complexes remain. Remains chromatin associated at the centromeres up to metaphase II. At anaphase II, dissociates from centromeres, allowing chromosomes segregation (By similarity) . .