NANO2 rabbit pAb

Domain: The Nanos-type zinc finger is composed of two C2HC motifs, each motif binding one molecule of zinc. It is essential for the translation repression activity of the protein. function: Required to support proliferation and self-renewal of proximal germ cells in males only. Probably regulates translation of specific mRNAs by associating with the 3'-UTR of mRNA targets. Essential for spermatogonia formation. similarity: Belongs to the nanos family. similarity: Contains 1 nanos-type zinc finger.

Product Specifications

Background

Domain:The Nanos-type zinc finger is composed of two C2HC motifs, each motif binding one molecule of zinc. It is essential for the translation repression activity of the protein., function:Required to support proliferation and self-renewal of proximal germ cells in males only. Probably regulates translation of specific mRNAs by associating with the 3'-UTR of mRNA targets. Essential for spermatogonia formation., similarity:Belongs to the nanos family., similarity:Contains 1 nanos-type zinc finger.

UniProt

P60321

Swiss Prot

P60321

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 10-90

Target

NANO2

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Buffer

-20°C/1 year

Molecular Weight

15kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

15kD

Fragment

IgG

Subcellular Location

Cytoplasm . Cytoplasm, P-body . Cytoplasm, perinuclear region . Localizes at P-bodies during gonocyte development (By similarity) . More abundant in perinuclear region of the cytoplasm of the germ cells of the adult testis. .