OSTCN rabbit pAb
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015],
Product Specifications
Background
UniProt
P02818
Swiss Prot
P02818
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein AA range: 31-80
Target
OSTCN
Clonality
Polyclonal
Source
Rabbit
Applications
WB IF; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
11kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
11kD
Fragment
IgG
Subcellular Location
Secreted.
Gene ID (Human)
632
Available Sizes
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