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LTBP1 rabbit pAb

Latent transforming growth factor beta binding protein 1 (LTBP1) Homo sapiens The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent Cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

Product Specifications

Background

Latent transforming growth factor beta binding protein 1 (LTBP1) Homo sapiens The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs) . The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

UniProt

Q14766

Swiss Prot

Q14766

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

189kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

189kD

Fragment

IgG

Subcellular Location

Secreted . Secreted, extracellular space, extracellular matrix .

Gene ID (Human)

4052

Available Sizes

Curated Selection

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