DNER rabbit pAb

Function: Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis. similarity: Contains 1 follistatin-like domain. similarity: Contains 10 EGF-like domains. subcellular location: Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region. subunit: Interacts with AP1G1. Interacts with NOTCH1. tissue specificity: Expressed in brain, spinal cord and adrenal gland.

Product Specifications

Background

Function:Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis., similarity:Contains 1 follistatin-like domain., similarity:Contains 10 EGF-like domains., subcellular location:Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region., subunit:Interacts with AP1G1. Interacts with NOTCH1., tissue specificity:Expressed in brain, spinal cord and adrenal gland.

UniProt

Q8NFT8

Swiss Prot

Q8NFT8

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

81kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

81kD

Fragment

IgG

Subcellular Location

Cell membrane; Single-pass type I membrane protein. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity) . .