PSD4 rabbit pAb

Function: Guanine nucleotide exchange factor for ARF6-like protein. Involved in membrane recycling. similarity: Contains 1 PH domain. similarity: Contains 1 SEC7 domain. subcellular location: Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures. tissue specificity: Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.

Product Specifications

Background

Function:Guanine nucleotide exchange factor for ARF6-like protein. Involved in membrane recycling., similarity:Contains 1 PH domain., similarity:Contains 1 SEC7 domain., subcellular location:Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures., tissue specificity:Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.

UniProt

Q8NDX1

Swiss Prot

Q8NDX1

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

116kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

116kD

Fragment

IgG

Subcellular Location

Cell membrane . Cell projection, ruffle membrane . In interphase associated with the plasma membrane, in particular with membrane ruffling regions (PubMed:23603394) . Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures (PubMed:12082148) . Recruited to membranes via phosphatidylinositol phosphate-binding (Probable) . .