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BC11B rabbit pAb

B-cell CLL/lymphoma 11B (BCL11B) Homo sapiens This gene encodes a C2H2-type Zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013],

Product Specifications

Background

B-cell CLL/lymphoma 11B (BCL11B) Homo sapiens This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013]

UniProt

Q9C0K0

Swiss Prot

Q9C0K0

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 570-650

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

98kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

98kD

Fragment

IgG

Subcellular Location

Nucleus .

Gene ID (Human)

64919

Available Sizes

Curated Selection

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