Tenifatecan
Product Specifications
UNSPSC Description
Tenifatecan (SN2310) is an injectable emulsion composed of vitamin E, a succinate derivative,
as well as 7-ethyl-10-hydroxycamptothecin (SN-38, the active metabolite of irinotecan). Tenifatecan (SN2310) possesses anticancer activity[1].
Target Antigen
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tenifatecan.html
Solubility
10 mM in DMSO
Smiles
CCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC=C(OC(CCC(OC6=C(C)C(C)=C(O[C@@](C)(CC7)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C7=C6C)=O)=O)C=C51
Molecular Weight
905.17
References & Citations
[1]Jean-Francois Marier, et al. Pharmacokinetics of SN2310, an injectable emulsion that incorporates a new derivative of SN-38 in patients with advanced solid tumors. J Pharm Sci. 2011 Oct;100(10):4536-45.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-14871/Tenifatecan-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-14871/
Clinical Information
Phase 1
CAS Number
850728-18-6
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