TSH3 rabbit pAb
This gene encodes a zinc-finger transcription factor that regulates smooth muscle cell differentiation in the developing urinary tract. Consistent with this role, mice in which this gene has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis. The encoded transcription factor comprises a gene silencing complex that inhibits caspase expression. Reduced expression of this gene and consequent caspase upregulation may be correlated with progression of Alzheimer's disease in human patients. [provided by RefSeq, Jul 2016],
Product Specifications
Background
UniProt
Q63HK5
Swiss Prot
Q63HK5
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
118kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
118kD
Fragment
IgG
Subcellular Location
Nucleus . Cell projection, growth cone . Colocalizes with APBB1 in axonal growth cone (By similarity) . Colocalizes with APBB1 in the nucleus. .
Gene ID (Human)
57616
Available Sizes
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