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MAGD1 rabbit pAb

This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Product Specifications

Background

This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt

Q9Y5V3

Swiss Prot

Q9Y5V3

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human protein . at AA range: 200-280

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

85kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

85kD

Fragment

IgG

Subcellular Location

Cytoplasm . Cell membrane ; Peripheral membrane protein . Nucleus . Expression shifts from the cytoplasm to the plasma membrane upon stimulation with NGF. .

Gene ID (Human)

9500

Available Sizes

Curated Selection

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