VA0D2 rabbit pAb

Function: Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis. similarity: Belongs to the V-ATPase V0D/AC39 subunit family. subunit: V-ATPase is an heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d). tissue specificity: Kidney, osteoclast and lung.

Product Specifications

Background

Function:Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis., similarity:Belongs to the V-ATPase V0D/AC39 subunit family., subunit:V-ATPase is an heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d) ., tissue specificity:Kidney, osteoclast and lung.

UniProt

Q8N8Y2

Swiss Prot

Q8N8Y2

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Target

VA0D2

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Buffer

-20°C/1 year

Molecular Weight

38kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

38kD

Fragment

IgG

Subcellular Location

Lysosomal membrane, early endosome, endosome membrane, membrane, apical plasma membrane, vacuolar proton-transporting V-type ATPase complex, phagocytic vesicle membrane, proton-transporting V-type ATPase, V0 domain, plasma membrane proton-transporting V