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UIMC1 rabbit pAb

Ubiquitin interaction motif containing 1 (UIMC1) Homo sapiens This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],

Product Specifications

Background

Ubiquitin interaction motif containing 1 (UIMC1) Homo sapiens This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

UniProt

Q96RL1

Swiss Prot

Q96RL1

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

79kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

79kD

Fragment

IgG

Subcellular Location

Nucleus . Localizes at sites of DNA damage at double-strand breaks (DSBs) .

Gene ID (Human)

51720

Available Sizes

Curated Selection

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