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TRRAP rabbit pAb

This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of this gene may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],

Product Specifications

Background

This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of this gene may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

UniProt

Q9Y4A5

Swiss Prot

Q9Y4A5

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Target

TRRAP

Clonality

Polyclonal

Source

Rabbit

Applications

IHC; IF

Concentration

1 mg/ml

Dilution

IHC-p 1:50-300

Buffer

-20°C/1 year

Molecular Weight

424kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

424kD

Fragment

IgG

Subcellular Location

Nucleus .

Gene ID (Human)

8295

Available Sizes

Curated Selection

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