TM1L1 rabbit pAb

Function: Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promotes FYN activation, possibly by disrupting intramolecular SH3-dependent interactions. PTM: Phosphorylated on tyrosines by FYN (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the TOM1 family. similarity: Contains 1 GAT domain. similarity: Contains 1 VHS domain. subunit: Interacts with FYN, GRB2 and PIK3R1 when phosphorylated.

Product Specifications

Background

Function:Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promotes FYN activation, possibly by disrupting intramolecular SH3-dependent interactions., PTM:Phosphorylated on tyrosines by FYN (By similarity) . Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the TOM1 family., similarity:Contains 1 GAT domain., similarity:Contains 1 VHS domain., subunit:Interacts with FYN, GRB2 and PIK3R1 when phosphorylated.

UniProt

O75674

Swiss Prot

O75674

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

52kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

52kD

Fragment

IgG

Subcellular Location

Golgi apparatus, Golgi stack. Endosome membrane . Cytoplasm . Membrane ; Peripheral membrane protein ; Cytoplasmic side . A small proportion is membrane-associated. .