SYT5 rabbit pAb
Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 [PubMed 7597049]). [supplied by OMIM, Feb 2011],
Product Specifications
Background
Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 [PubMed 7597049]) .[supplied by OMIM, Feb 2011]
UniProt
O00445
Swiss Prot
O00445
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Target
SYT5
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
42kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
42kD
Fragment
IgG
Subcellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass membrane protein . Recycling endosome membrane ; Single-pass membrane protein . In mast cells, localizes to the endocytic recycling compartment. .
Gene ID (Human)
6861
Available Sizes
Curated Selection
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