SC6A3 rabbit pAb

This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence. [provided by RefSeq, Nov 2009],

Product Specifications

Background

UniProt

Q01959

Swiss Prot

Q01959

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

68kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

68kD

Fragment

IgG

Subcellular Location

Cell membrane ; Multi-pass membrane protein . Cell projection, neuron projection . Cell projection, axon . Localizes to neurite tips in neuronal cells (By similarity) . Colocalizes with SEPTIN4 at axon terminals, especially at the varicosities (By similarity) . .