RBBP6 rabbit pAb
The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Product Specifications
Background
The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt
Q7Z6E9
Swiss Prot
Q7Z6E9
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 270-350
Target
RBBP6
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
197kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
197kD
Fragment
IgG
Subcellular Location
Nucleus, nucleolus. Chromosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Colocalizes with mitotic chromosomes. Colocalizes with NEK6 in the centrosome.
Gene ID (Human)
5930
Available Sizes
Curated Selection
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