BD1L1 rabbit pAb
Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2-dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBXO18/FBH1 and BLM.
Product Specifications
Background
Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2-dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBXO18/FBH1 and BLM.
UniProt
Q8NFC6
Swiss Prot
Q8NFC6
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 1280-1360
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF
Concentration
1 mg/ml
Dilution
IHC-p 1:50-300
Molecular Weight
335kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
335kD
Fragment
IgG
Subcellular Location
Chromosome . Localizes at replication forks: following DNA damage, localizes to damaged replication forks undergoing resection. .
Gene ID (Human)
259282
Available Sizes
Curated Selection
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