PREX1 rabbit pAb
Phosphatidylinositol-3, 4, 5-trisphosphate dependent Rac exchange factor 1 (PREX1) Homo sapiens The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3, 4, 5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
Q8TCU6
Swiss Prot
Q8TCU6
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 340-420
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
182kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
182kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytosol. Cell membrane. Mainly cytosolic. Some amount is apparently associated to the plasma membrane.
Gene ID (Human)
57580
Available Sizes
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