UNC5C rabbit pAb

This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region. [provided by RefSeq, Jul 2008],

Product Specifications

Background

This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig) -like domains and 2 type I thrombospondin motifs in the extracellular region. [provided by RefSeq, Jul 2008]

UniProt

O95185

Swiss Prot

O95185

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human protein . at AA range: 60-140

Target

UNC5C

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Buffer

-20°C/1 year

Molecular Weight

102kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

102kD

Fragment

IgG

Subcellular Location

Cell membrane ; Single-pass type I membrane protein . Cell surface . Cell junction, synapse, synaptosome . Cell projection, axon . Cell projection, dendrite . Cell projection, growth cone . Cell projection, lamellipodium . Cell projection, filopodium .