LIPA1 rabbit pAb
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
Q13136
Swiss Prot
Q13136
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 980-1060
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
132kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
132kD
Fragment
IgG
Subcellular Location
Cytoplasm . Colocalizes with PTPRF at the ends of focal adhesions most proximal to the cell nucleus.
Gene ID (Human)
8500
Available Sizes
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