GMDS rabbit pAb
GDP-mannose 4, 6-dehydratase (GMD; EC 4. 2. 1. 47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3, 5-epimerase, 4-reductase, designated FX in humans (MIM 137020). [supplied by OMIM, Aug 2009],
Product Specifications
Background
GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020) .[supplied by OMIM, Aug 2009]
UniProt
O60547
Swiss Prot
O60547
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Target
GMDS
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
40kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
40kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytosol, extracellular exosome
Gene ID (Human)
2762
Available Sizes
Curated Selection
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