EDEM1 rabbit pAb
Function: Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity. similarity: Belongs to the glycosyl hydrolase 47 family. subunit: Interacts with DERL2 and DERL3.
Product Specifications
Background
Function:Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity., similarity:Belongs to the glycosyl hydrolase 47 family., subunit:Interacts with DERL2 and DERL3.
UniProt
Q92611
Swiss Prot
Q92611
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
72kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
72kD
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Single-pass type II membrane protein .
Gene ID (Human)
9695
Available Sizes
Curated Selection
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