MARH8 rabbit pAb
MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6. 3. 2. 19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al. 2003 [PubMed 12582153]; Bartee et al. 2004 [PubMed 14722266]). [supplied by OMIM, Apr 2010],
Product Specifications
Background
MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19) . MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153]; Bartee et al., 2004 [PubMed 14722266]) .[supplied by OMIM, Apr 2010]
UniProt
Q5T0T0
Swiss Prot
Q5T0T0
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Target
MARH8
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
32kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
32kD
Fragment
IgG
Subcellular Location
Cytoplasmic vesicle membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Early endosome membrane ; Multi-pass membrane protein .
Gene ID (Human)
220972
Available Sizes
Curated Selection
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