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DOCK7 rabbit pAb

The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that plays a role in axon formation and neuronal polarization. The encoded protein displays GEF activity toward RAC1 and RAC3 Rho small GTPases but not toward CDC42. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012],

Product Specifications

Background

The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that plays a role in axon formation and neuronal polarization. The encoded protein displays GEF activity toward RAC1 and RAC3 Rho small GTPases but not toward CDC42. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]

UniProt

Q96N67

Swiss Prot

Q96N67

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

235kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

235kD

Fragment

IgG

Subcellular Location

Cell projection, axon . Enriched in the developing axons of hippocampal neurons.

Gene ID (Human)

85440

Available Sizes

Curated Selection

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