CHD9 rabbit pAb

Function: Acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors. Proposed to be a ATP-dependent chromatin remodeling protein. Has DNA-dependent ATPase activity and binds to A/T-rich DNA. Associates with A/T-rich regulatory regions in promoters of genes that participate in the differentiation of progenitors during osteogenesis. PTM: Phosphorylated on serine and tyrosine residues. sequence Caution: Wrong choice of frame. similarity: Belongs to the SNF2/RAD54 helicase family. similarity: Contains 1 helicase ATP-binding domain. similarity: Contains 1 helicase C-terminal domain. similarity: Contains 2 chromo domains. subunit: Interacts with PPARA. Probably interacts with ESR1 and NR1I3. tissue specificity: Widely expressed at low levels. In bone marrow, expression is restricted to osteoprogenitor cells adjacent to mature osteoblasts.