CLCN5 rabbit pAb

Chloride voltage-gated channel 5 (CLCN5) Homo sapiens This gene encodes a member of the ClC family of Chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013],

Product Specifications

Background

Chloride voltage-gated channel 5 (CLCN5) Homo sapiens This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013]

UniProt

P51795

Swiss Prot

P51795

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

82kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

82kD

Fragment

IgG

Subcellular Location

Golgi apparatus membrane ; Multi-pass membrane protein . Endosome membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein .