PDE2A rabbit pAb

Alternative products: Additional isoforms seem to exist. Experimental confirmation may be lacking for some isoforms, Catalytic activity: Nucleoside 3', 5'-cyclic phosphate + H (2)O = nucleoside 5'-phosphate. function: Hydrolyzes both cyclic AMP (cAMP) and cyclic GMP (cGMP). similarity: Belongs to the cyclic nucleotide phosphodiesterase family. similarity: Contains 2 GAF domains. subunit: Homodimer. tissue specificity: Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas.

Product Specifications

Background

Alternative products:Additional isoforms seem to exist. Experimental confirmation may be lacking for some isoforms, catalytic activity:Nucleoside 3',5'-cyclic phosphate + H (2) O = nucleoside 5'-phosphate., function:Hydrolyzes both cyclic AMP (cAMP) and cyclic GMP (cGMP) ., similarity:Belongs to the cyclic nucleotide phosphodiesterase family., similarity:Contains 2 GAF domains., subunit:Homodimer., tissue specificity:Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas.

UniProt

O00408

Swiss Prot

O00408

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from part region of human protein

Target

PDE2A

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Buffer

-20°C/1 year

Molecular Weight

103kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

103kD

Fragment

IgG

Subcellular Location

[Isoform PDE2A3]: Cell membrane ; Lipid-anchor .; [Isoform PDE2A2]: Mitochondrion matrix . Mitochondrion inner membrane . Mitochondrion outer membrane .; [Isoform PDE2A1]: Cytoplasm .; [Isoform 5]: Mitochondrion .