CTSR4 rabbit pAb

Function: Voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. Controls calcium entry to mediate the hyperactivated motility, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. Activated by intracellular alkalinization. similarity: Belongs to the cation channel sperm-associated family. subunit: Heterotetramer; possibly composed of CATSPER1, CATSPER2, CATSPER3 and CATSPER4 (Potential). Interacts with CATSPER1. tissue specificity: Testis-specific. Specifically present in the principal piece of sperm tail.