CAPS2 rabbit pAb

Calcium dependent secretion activator 2 (CADPS2) Homo sapiens This gene encodes a member of the calcium-dependent activator of secretion (CAPS) protein family, which are calcium binding proteins that regulate the exocytosis of synaptic and dense-core vesicles in neurons and neuroendocrine cells. Mutations in this gene may contribute to autism susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2009],

Product Specifications

Background

UniProt

Q86UW7

Swiss Prot

Q86UW7

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

142kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

142kD

Fragment

IgG

Subcellular Location

Cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell junction, synapse. Membrane-associated to vesicles. Strongly enriched in synaptic fractions. Probably localizes to different vesicles compared to CADPS. Enriched on vesicular structures in the parallel fiber terminal of granule cells that are distinct from synaptic vesicles.