CTNL1 rabbit pAb

Function: May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1). induction: Down-regulated in cancer pancreatic cells undergoing differentiation and apoptosis. similarity: Belongs to the vinculin/alpha-catenin family. subunit: Interacts with ARHGEF1. tissue specificity: Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.