AFF4 rabbit pAb
The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins (5;11) (q31;q31q23). [provided by RefSeq, Oct 2011],
Product Specifications
Background
The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins (5;11) (q31; q31q23) . [provided by RefSeq, Oct 2011]
UniProt
Q9UHB7
Swiss Prot
Q9UHB7
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 30-110
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
127kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
127kD
Fragment
IgG
Subcellular Location
Nucleus . Associates to transcriptionally active chromatin but not at snRNA genes. .
Gene ID (Human)
27125
Available Sizes
Curated Selection
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NALP11 (NACHT, LRR and PYD Domains-containing Protein 11, Nucleotide-binding Oligomerization Domain Protein 17, PAAD-and NACHT Domain-containing Protein 10, PYRIN-containing APAF1-like Protein 6, NLRP11, NOD17, PAN10, PYPAF6)
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