KAT6A rabbit pAb
This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with autosomal dominant mental retardation-32. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],
Product Specifications
Background
UniProt
Q92794
Swiss Prot
Q92794
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human protein . at AA range: 160-240
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
220kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
220kD
Fragment
IgG
Subcellular Location
Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm. Nucleus, PML body. Recruited into PML body after DNA damage.
Gene ID (Human)
7994
Available Sizes
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