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EPS8 rabbit pAb

This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008],

Product Specifications

Background

This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]

UniProt

Q12929

Swiss Prot

Q12929

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 130-210

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

90kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

90kD

Fragment

IgG

Subcellular Location

Cytoplasm, cell cortex . Cell projection, ruffle membrane . Cell projection, growth cone . Cell projection, stereocilium . Cell junction, synapse, synaptosome . Localizes at the tips of the stereocilia of the inner and outer hair cells (By similarity) . Localizes to the midzone of dividing cells. .

Gene ID (Human)

2059

Available Sizes

Curated Selection

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