C8 α rabbit pAb
C8 is a component of the complement system and contains three polypeptides, alpha, beta and gamma. This gene encodes the alpha subunit of C8. C8 participates in the formation of the membrane attack complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause complement C8 alpha-gamma deficiency. [provided by RefSeq, Nov 2008],
Product Specifications
Background
Product Name Alternative
Complement component C8 alpha chain (Complement component 8 subunit alpha)
UniProt
P07357
Swiss Prot
P07357
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human C8 α. at AA range: 201-250
Target
C8 α
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000, ELISA 1:10000-20000
Buffer
-20°C/1 year
Molecular Weight
60kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
60kD
Fragment
IgG
Subcellular Location
Secreted. Cell membrane; Multi-pass membrane protein. Secreted as soluble protein. Inserts into the cell membrane of target cells.
Other Product Names
Complement component C8 alpha chain (Complement component 8 subunit alpha)
Gene ID (Human)
731
Available Sizes
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