ASPP1 rabbit pAb
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
Q96KQ4
Swiss Prot
Q96KQ4
Reactivity
Human; Rat; Mouse
Immunogen
Synthetic peptide from human protein at AA range: 630-680
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
IHC-p 1:50-200, ELISA 1:10000-20000
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus . Predominantly cytoplasmic. Some fraction is nuclear.
Other Product Names
Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B)
Gene ID (Human)
23368
Available Sizes
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