HDGF rabbit pAb

This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of this gene enhance the growth of many tumors. This gene was thought initially to be located on chromosome X; however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2016],

Product Specifications

Background

UniProt

P51858

Swiss Prot

P51858

Reactivity

Human; Rat; Mouse

Immunogen

Synthetic peptide from human protein at AA range: 141-190

Clonality

Polyclonal

Source

Rabbit

Applications

IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

IHC-p 1:50-200, ELISA 1:10000-20000

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

[Isoform 1]: Nucleus . Cytoplasm . Secreted, extracellular exosome . Secreted by exosomes and is located inside the exosome (PubMed:27926477) . May also be secreted as free protein via an as yet unknown pathway (PubMed:27926477) . .; [Isoform 2]: Nucleus . Cytoplasm . Secreted, extracellular exosome . Secreted by exosomes and is located on the outer exosome surface. .; [Isoform 3]: Nucleus . Cytoplasm . Secreted, extracellular exosome . Secreted by exosomes and is located on the outer exosome surface. .