PBP rabbit pAb

The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. [provided by RefSeq, Nov 2014],

Product Specifications

Background

UniProt

P02775

Swiss Prot

P02775

Reactivity

Human; Rat; Mouse

Immunogen

Synthetic peptide from human protein at AA range: 71-120

Clonality

Polyclonal

Source

Rabbit

Applications

IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

IHC-p 1:50-200, ELISA 1:10000-20000

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Secreted.

Other Product Names

Platelet basic protein (PBP; C-X-C motif chemokine 7; Leukocyte-derived growth factor; LDGF; Macrophage-derived growth factor; MDGF; Small-inducible cytokine B7) [Cleaved into: Connective tissue-activating peptide III (CTAP-III; LA-PF4; Low-affinity platelet factor IV) ; TC-2; Connective tissue-activating peptide III (1-81; CTAP-III (1-81) ) ; Beta-thromboglobulin (Beta-TG) ; Neutrophil-activating peptide 2 (74; NAP-2 (74) ) ; Neutrophil-activating peptide 2 (73; NAP-2 (73) ) ; Neutrophil-activating peptide 2 (NAP-2) ; TC-1; Neutrophil-activating peptide 2 (1-66; NAP-2 (1-66) ) ; Neutrophil-activating peptide 2 (1-63; NAP-2 (1-63) ) ]