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Histone H2B (Acetyl Lys24/25) rabbit pAb

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a testis/sperm-specific member of the histone H2B family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015],

Product Specifications

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a testis/sperm-specific member of the histone H2B family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015]

Synonyms

H2BFS; Histone H2B type F-S; Histone H2B.s; H2B/s;H2BK2425AC

Gene ID

255626

UniProt

Q96A08/P33778/P62807

Cellular Locus

Nucleus. Chromosome.

Host

Rabbit

Species Reactivity

Human,Rat,Mouse

Reactivity

Human; Rat; Mouse

Immunogen

Synthetic Acetyl peptide from human protein at AA range: 24/25

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000, ELISA 1:10000-20000

Molecular Weight

15kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8626-1.pdf

Observed Molecular Weight

15 kD

Subcellular Location

Nucleus . Chromosome .

Other Product Names

H2BFS; Histone H2B type F-S; Histone H2B.s; H2B/s; H2BK2425AC

Gene ID (Human)

255626

SwissProt (Human)

Q96A08/P33778/P62807

Available Sizes

Curated Selection

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